About Gut-Research

Research group within the Tytgat Institute for Liver and Intestinal Research in Amsterdam

Projects

Projects by us

At Gut-Research, we specialize in advancing the understanding and treatment of gastrointestinal diseases through innovative research and clinical collaboration. Our expert team and state-of-the-art facilities enable us to offer high-quality, impactful services across four main areas: intestinal microbiota and health, inflammatory bowel disease (IBD) and personalized medicine, colorectal cancer treatment, and intestinal health for newborns.

Our Capabilities

Gut-Research is equipped with cutting-edge technology and a team of leading scientists and clinicians. Our capabilities include advanced research techniques, extensive biobanking, and robust preclinical and clinical trial support. We specialize in areas such as microbiota analysis, inflammatory bowel disease (IBD) research, irritable bowel syndrome (IBS) studies, and pediatric gastroenterology. Our collaborative approach and dedication to excellence make us a trusted partner in gastrointestinal research.

Project: Complications in Crohn's Disease - Fistulae Research

This project focuses on identifying biomarker profiles to predict treatment responses in patients with perianal fistulizing Crohn's disease. By developing a precision medicine approach, the research aims to improve treatment outcomes and qualify of life for those affected by this severe complication.
See project details
Project: IBD Methylomic and OMICROHN Trial

This trial aims to uncover the epigenetic factors influencing inflammatory bowel disease (IBD). By analyzing methylomic changes, this project seeks to provide new insights into IBD progression and potential personalized treatments.
More about Methylomic
Project: Anastomotic leakage (AL)

AL is a serious complication following colorectal surgery. This study aims to assess AL by investigating the morphological, cellular, and molecular changes in anastomotic tissue, with the goal of improving patient outcomes. Supported by ZonMW.
More about ZonMW
Project: GROWTH 2020-2024

Metaryl is an EU JPI funded project that aims to study how the nutritional component tryptophan affect wound healing and infection in diabetes. First, we study how tryptophan metabolites affect the development of wound infections. Second, we determine how inflammation of the fat tissue in the abdomen plays a role in the development of type2 diabetes. The GROWTH program, part of the European Industrial Doctorates (EID), involves 10 PhD students developing biomarkers and personalized nutritional interventions for intestinal failure in neonates and preterm infants. By working with both academic and non-academic partners, the program bridges the gap between research and clinical applications. Utilizing over 17,000 fecal samples from premature infants, GROWTH aims to improve early intestinal development and reduce neonatal health risks.
More about GROWTH EID

Partner With Us

At Gut-Research, we are committed to driving innovation in gastrointestinal research through collaboration with academic institutions, healthcare providers, and industry partners. We invite you to explore partnership opportunities and learn how our expertise can support your research and clinical development goals.