About Gut-Research

Research group within the Tytgat Institute for Liver and Intestinal Research in Amsterdam

Intestinal microbiota and health

Service Overview

At Gut-Research, we specialize in studying the complex interactions between gut microbiota and human health, with a focus on gastrointestinal diseases like inflammatory bowel disease (IBD) and colorectal cancer. Our research aims to uncover how microorganisms influence gut health, immunity, and overall well-being. Utilizing cutting-edge sequencing technologies and bioinformatics tools, we deliver comprehensive insights that drive innovative treatments and therapeutic developments.

We are deeply connected with the Microbiota Center Amsterdam (MiCA), co-founded by Wouter de Jonge alongside Max Nieuwdorp and Joost Wiersinga. MiCA is a core facility at Amsterdam UMC that offers a full suite of microbiota analysis services, including DNA isolation, gene sequencing, bioinformatics, and study design support. Our collaboration with MiCA enables us to leverage the latest technology for our research projects, ensuring fast and precise analysis.

Our Capabilities

Gut-Research offers a wide range of advanced services for microbiota analysis. Our expert team and state-of-the-art facilities allow us to conduct in-depth studies on the role of microbiota in both health and disease. Key capabilities include:

  • DNA isolation and sequencing: We use cutting-edge techniques to isolate and sequence microbiota DNA, delivering high-resolution data on microbial composition and function.

  • Bioinformatics analysis: Our bioinformatics team employs advanced algorithms and tools to analyze sequencing data, providing deep insights into microbial communities and their interactions.

  • Microbiota-host interaction studies: We investigate how microbiota interact with host tissues, particularly focusing on how these relationships influence gut health and disease progression.

  • Personalized microbiota therapeutics: Based on our findings, we develop personalized therapeutic strategies aimed at modulating the microbiota to improve health outcomes, particularly in conditions like IBD and colorectal cancer.

Our research in intestinal microbiota and health spans across various gastrointestinal diseases, including IBD, necrotizing enterocolitis (NEC), irritable bowel syndrome (IBS), postoperative ileus, and anastomotic leakage. Our partnership with MiCA provides fast, reliable access to microbiota analysis, ensuring that our research projects have the most up-to-date data available.

As part of this national project, we work to understand the microbiome's role in health and disease using advanced technologies. For more information, visit HoloMicroBiome.
In partnership with the METAHEALTH project, we explore microbiome data to better understand its influence on chronic diseases. More details can be found at METAHEALTH.
We collaborate with AIBiomics, an Amsterdam UMC spin-off, which focuses on rapid microbiome testing using AI-powered analysis. AIBiomics develops a mobile health app to analyze gut microbiota in real-time, with a focus on chronic bowel disease, colorectal cancer, pediatrics, and diabetes. Learn more at AIBiomics.

Partner with us in Microbiota Research

Gut-Research is dedicated to advancing the field of microbiota research through collaboration. We invite academic institutions, healthcare providers, and industry partners to join us in exploring the role of microbiota in health and disease. By partnering with us, you gain access to our cutting-edge technology, expert team, and comprehensive services.

Together with MiCA, we can uncover new insights and develop innovative therapies that harness the power of microbiota to improve patient outcomes. Contact us today to learn more about collaboration opportunities and how Gut-Research can support your microbiota research projects.